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曲美他嗪对冠心病合并慢性充血性心力衰竭患者的临床疗效观察 被引量:14

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摘要 目的观察曲美他嗪对冠心病合并慢性充血性心力衰竭(CHF)患者的临床疗效。方法对确诊为冠心病并CHF 60例患者,随机分为治疗组和对照组,两组均给予常规抗心力衰竭治疗,治疗组还给予曲美他嗪20 mg,3次/d。观察治疗48周后的左心室功能分级及左心室收缩末容积指数(LVESVI)、左室舒张末容积指数(LVEDVI)和左室射向分数(LVEF)。结果治疗组治疗后的左心室功能改善临床总有效率达90%,较对照组63.33%显著提高(P<0.05),治疗后与治疗前相比,LVESVI、LVEDVI和LVEF均有显著改善(P<0.01),治疗组与对照组比较差异有显著意义(P<0.05)。结论常规治疗冠心病合并CHF基础上,加用曲美他嗪可进一步改善患者的心功能。
作者 田志斌
出处 《中国医学创新》 CAS 2011年第16期57-58,共2页 Medical Innovation of China
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