摘要
目的:优选健肾片的提取工艺。方法:考察黄芪的形状对黄芪甲苷提取率的影响,并采用正交试验法,以提取液中黄芪甲苷、淫羊藿苷的得率和干膏率为考察指标,考察加水量、提取时间和提取次数3个因素对提取结果的影响。结果:最佳提取工艺为加8倍量水提取2次,每次1.5 h,黄芪药材炮制的形状为段长(5~10 mm)。结论:该工艺合理可行,含量测定方法稳定可靠。
Objective:To optimize the extraction technology for Jianshen tablet.Method:The shape of Radix Astragalus was studied on the content of astragaloside Ⅳ and orthogonal test was used for studying the effect of water volume,extraction time and times on the content of icariin,astragaloside Ⅳ and solid.Result:The optimal extraction process was as follows:with 8 times of water extracted twice,each time for 1.5 h.The processing method of Radix Astragali was cutting for about 5-10 mm.Conclusion:The extraction process is reasonable and feasible.The method of content determination is accurate and reliable.
出处
《中国实验方剂学杂志》
CAS
北大核心
2011年第11期13-16,共4页
Chinese Journal of Experimental Traditional Medical Formulae
基金
重大新药创制--创新中药中试放大研究技术平台(2009ZX09313-032)
关键词
健肾片
提取工艺
正交试验
淫羊藿苷
黄芪甲苷
Jianshen tablet
extraction technology
orthogonal test
icariin
astragaloside Ⅳ