朱砂根化学成分和药理作用研究进展

Development of Chemical and Pharmacological of Ardisia crenata

通过查阅国内外研究文献,对近10年朱砂根化学成分及药理作用研究进行介绍。朱砂根中含有三萜皂苷、香豆素类、挥发油、酚类、醌类、强心苷、氨基酸、糖类等多种化合物。其有效成分除能够止咳平喘、抗炎抗菌外,具有抗肿瘤活性,抗生育、抑制血小板凝聚、降低血压、收缩子宫、cAMP磷酸二酯酶抑制作用等多方面作用。朱砂根具有多种生理活性,对其化学成分和生物活性的深入研究表明朱砂根对于治疗多种疾病具有良好的开发利用价值。

This paper presented a review of chemical and pharmacological of Ardisia crenata in nearly ten years on the basis of consulting plenty of domestic and foreign literature.The research indicated that A.crenata contains triterpenoid saponins,coumarins,volatile oil,phenols,quinone,cardiac glycoside,organic acid,saccharide etc.A.crenata was reported to possess relieving cough and asthma,anti-inflammatory,antibacterial,antineoplastic,antifertility,anticoagulant,lower blood pressure,triggering uterine contractions,cAMP phosphodiesterase inhibitory effect.The purpose of this study was to elaborate the research of chemical composition and biological activity of A.crenata,The in-depth research on A.crenata appears to have highly worth development and apply for the therapy of diseases.