基于铁催化的C-H键活化构建C-C键的研究进展

Iron catalyzed C-C bond formation via C-H activation

过渡金属催化的C-H键活化及在此基础上的C-C键形成的反应因其高原子经济性和高效的合成效率而备受人们的关注.铁元素具有含量丰富、廉价、易得、环境友好等优点,在催化反应中得到了越来越广泛的应用.近几年来,人们关于Fe催化的C-H键活化构建C-C键反应的研究也取得了一定的进展.本文对铁催化的C-H键活化构建C-C键的最新研究进展作了综述,并且按照铁催化剂的不同价态进行了分类归纳,也对催化机理进行了阐述与总结.

Transition metal-catalyzed C-H bond activation followed by C-C bond formation has attracted great attention due to its high synthetic efficiency and atom economy.Iron as one of the most abundant metals on earth,which offers several advantages such as inexpensive,readily available and environmentally friendly,has been increasingly explored in modern catalysis.In particular,recent studies on Fe catalysis have led to much progress in the direct formation of C-C bonds through iron-catalyzed C-H bond activation.In this paper,the recent advances in iron-catalyzed the C-C bond formation via C-H bond activation were summarized and categorized according to the oxidation states of the iron catalysts.The mechanisms of these transformations were also included.