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膀胱癌CD4^＋CD25^highFoxp3^＋调节性T淋巴细胞数量和分布及Foxp3基因表达与肿瘤分期的相关性 被引量：4

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摘要 我们用四色流式细胞术准确界定CD4^＋CD25^highFoxp3^＋Treg，实时荧光定量聚合酶链反应（PCR）技术检测Treg的特异性功能基因Foxp3mRNA的表达水平，分析不同分期膀胱癌患者的该群细胞数量、膀胱癌不同部位的分布及Foxp3的表达差异与膀胱癌临床TNM分期的关系，探讨Treg在膀胱癌患者中表达水平及临床意义。
作者 魏明 酒涛 涂玲 梁颖红 刘佳 张俊华 张俊峰
机构地区 郑州大学第五附属医院
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2011年第6期1005-1006,共2页 Chinese Journal of Experimental Surgery
关键词 FOXP3 肿瘤分期 细胞数量 膀胱癌 基因表达 实时荧光定量聚合酶链反应 相关性 调节性
分类号 R737.14 [医药卫生—肿瘤]
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参考文献9

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同被引文献58

  • 1梁启廉,陈小东,王三明,李建文,黄冰,郑朝晖,陈雪松.VEGF和抑癌基因maspin在胃癌组织中的表达及意义[J].第三军医大学学报,2007,29(14):1416-1418. 被引量：18
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中华实验外科杂志
2011年 第6期

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