水杨酸分子印迹电化学传感器的制备及其性能研究

Preparation and characteristics of electrochemical sensor for salicylic acid based on molecularly imprinted polymers

以水杨酸作为模板分子,通过原位聚合法,在玻碳电极表面合成了水杨酸分子印迹聚合物膜,并用方波伏安法对该印迹电极进行了分析研究。当吸附时间为7 min时,印迹电极对水杨酸浓度响应的线性范围为1.0×10-5～2.6×10-4mol/L,检出限(S/N=3)为2.0×10-6mol/L,同一支印迹电极对水杨酸响应值的RSD为3.7%(n=7),该印迹电极对水杨酸具有良好的选择性,对结构相似的对羟基苯甲酸和对氨基苯甲酸的选择性系数分别为12和6.9。使用该分子印迹膜传感器对实际化妆品样品进行分析,加标回收率为99.9%～106.7%。

A molecularly imprinted polymer（MIP） film was synthesized on the surface of a glassy carbon electrode with the salicylic acid（SA） as template.Electrochemical oxidation behaviors of SA on the imprinted electrode were investigated by square wave voltammetry.As the incubation time of 7 min,the peak current was proportional to the concentration of SA in the range from 1.0×10-5 to 2.6×10-4 mol/L with a detection limit of 2.0×10-6 mol/L（S/N=3）.The RSD of the peak current was 3.7 %（n = 7）.The imprinted electrode displayed good specificity.The selective coefficients of structural analogs were 12 and 6.9 for p-hydroxybenzoic acid and p-aminobenzoic acid,respectively.The MIP sensors had been used to determine SA in cosmetic samples with recoveries between 99.9% and 106.7%.