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Musashil和Notch信号通路在脑缺血后神经发生中的作用 被引量：1

The roles of Musashil and Notch signaling pathways in neurogenesis after cerebral ischemia
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摘要 Musashil是一种进化保守的RNA结合蛋白，在维持干细胞状态、分化以及肿瘤发生方面起重要作用。Notch信号通路在脑缺血后神经干细胞的增殖中起重要作用。文章简要介绍Musashil和Notch的结构和分子生物学特征，并对Musashil和Notch信号通路在脑缺血再灌注后神经发生中的相互作用进行了综述。 Musashil is an evolutionarily conserved RNA binding protein. It plays an important role in the aspects of maintaining stem cell state, differentiation and tumorigesis. Notch signal pathway plays an important role in the proliferation of neural stem cells after cerebral ischemia. This article briefly introduces the structure and molecular characteristics of Musashil and Notch, and reviews the interaction in the neurogenesis of Musashil and Notch signaling pathway after cerebral ischemic reperfusion.
作者 刘学娟 杨金升
机构地区 兰州军区兰州总医院神经内科
出处 《国际脑血管病杂志》 北大核心 2011年第5期397-400,共4页 International Journal of Cerebrovascular Diseases
关键词 神经组织蛋白 RNA结合蛋白 MSll蛋白 人 受体 NOTCH 脑缺血 神经再生 Nerve tissue proteins RNA-binding proteins MSI1 protein, human Receptors, Notch Brain ischemia Nerve re^neration
分类号 R-2 [医药卫生]
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参考文献26

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同被引文献12

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  • 7张正洪,肖红菊,席刚明,曲鹏,方秀斌.CGRP对局灶性脑缺血再灌注大鼠顶叶皮质CREB和p-CREB的上调作用[J].中国病理生理杂志,2008,24(1):28-31. 被引量：6
  • 8郭怡菁,张志珺,王少华,隋毓秀,孙奕,滕皋军.局灶性缺血性脑卒中大鼠海马Notch信号通路的动态表达[J].中华医学杂志,2008,88(39):2803-2805. 被引量：7
  • 9王力峰,陈丽,彭道珍,钟茂林.Notch信号通路在脑缺血损伤中的作用机制研究进展[J].实用医学杂志,2011,27(23):4337-4338. 被引量：3
  • 10陈丽,叶军明,彭道珍,钟茂林,王力峰,周树宝,郭锐,占丽芳.脑缺血预处理中大鼠海马Notch信号通路的变化[J].赣南医学院学报,2012,32(1):10-12. 被引量：7

引证文献1

国际脑血管病杂志
2011年 第5期

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