摘要
目的了解血清泌乳素(PRL)在慢性肾脏病不同分期男性病人的水平变化。方法纳入2000～2010年慢性肾脏病(CKD)男性病人110例,通过测量肾功能和同期的血清PRL,并应用简化MDRD方程计算的肾小球滤过率(GFR),按照GFR的水平将慢性肾脏病分为5期,分析对照不同分期的慢性肾脏病病人血清PRL水平。结果随着CKD分期的进展,PRL水平显著上升,CKD各分期间PRL水平比较差异有统计学意义。结论在不同分期的CKD患者,其催乳素水平有显著差异,从CKDl期至CKD5期,高泌乳素血症的发生率逐渐增高,提示PRL可作为CKD患者肾脏病情动态变化的重要指标之一。
Objective To explore serum prolactin level in patients with chronic kidney disease.Methods 110 cases of male CKD patients in our hospital between 2000 and 2010 were taken in the experiment.Their renal and serum prolactin were measured.Results Higher level of serum prolactin was associated with the stage of CKD stage by stage.Conclusion A significantly negative correlation was discovered between serum prolactin level and the level of glomerular filtration rate.
出处
《当代医学》
2011年第17期102-103,共2页
Contemporary Medicine
