胰腺癌围手术期局部化疗与疗效观察

Observation of local chemical therapy for patients with pancreatic carcinoma in perioperative period

目的 观察胰腺癌的局部化疗效果。方法 13例胰腺癌患者在B超引导下,经皮或/和术中穿刺胰癌肿块注药化疗共47例次。结果 本组除2例晚期胰癌分别存活82天和38天后死于多器官功能衰竭(MOF)外,均好转治愈(89.6％)。结论 该方法不仅提高了胰腺癌的好转治愈率和生活质量,且不同程度地延长了存活时间,对手术切除困难或无法根治者增加了新的治疗手段。

Objective To observe the effect of local chemical therapy on patients with pancreatic carcinoma. Methods Thirteen patients with pancreatic careinoma in perioperative period were punctured and injected with obliterants for 47 times. All procedures were guided by B ultrasound and pancreas masses were punctured percuta-neously^jr operatively (including injection of obliterants in operation for 5 times). Results Two patients dying of MOF survived of 82 and 38 days respectively after operation, and the others were cured (84. 6%). Conclusion Local chemical therapy can enhance treatment effect of pancreatic carcinoma, and is a comparatively new treatment method.