摘要
目的:探讨中药封脐疗法对慢性荨麻疹(CU)临床近期、远期疗效,以及对患者细胞免疫功能的影响。方法:对照组口服氯雷他定分散片(原研),治疗组加用中药封脐,观察疗效和治疗前后外周血T淋巴细胞亚群、外周血EOS计数和血清嗜酸性阳离子蛋白(ECP)的变化。结果:治疗后,治疗组CD4+升高、CD8+下降,CD4+/CD8+比值升高,ECP计数下降。治疗后6个月随访,治疗组复发率明显低于对照组。结论:中药封脐疗法可增强慢性荨麻疹患者细胞免疫功能,提高疗效,减少复发。
Objective: To observe the immunity and clinical therapeutic effect of Chronic Urticaria with external application to navel in the treatment.Methods: 65 patients were divided into two groups at random.The treatment group were treated with external application to navel,the control group took Loratadine Dispersible Tablets.The EOS count,the T-lymopholyte subsynecology,the ECP and the function of liver and kidney were detected and compared before and after treated.The clinical therapeutic effect and the recurrence rate were compared as well.Results:After the treatment,there were significant differences about the ECP count(P0.05).It is also found that the higher difference about CD4 percentand CD4/CD8 rations(P0.05).The rate of recurrence in the treatment group is lower than the other.Conclusion: The external application to navel in the treatment can adjust the imbalance of Th1/Th2 rations,regulate anaphylaxis and allergy,reduce the rate of recurrence and enhance immunity function.
出处
《中华中医药学刊》
CAS
2011年第6期1426-1428,共3页
Chinese Archives of Traditional Chinese Medicine
关键词
中药封脐
免疫功能
T细胞亚群
ECP
复发
external application to navel
T-lymopholyte subsynecology
recurrence
ECP
immunity function