摘要
目的:探讨高强度聚焦超声(HIFU)治疗晚期胰腺癌患者的疗效与护理方法。方法:将36例晚期胰腺癌患者随机分为治疗组21例和对照组15例,治疗组应用FEP-BY02型HIFU肿瘤治疗机治疗,对照组实施支持疗法。通过比较两组临床症状、实验室检查、影像学变化、并发症等情况,观察HIFU的治疗效果和安全性。结果:治疗组90.5%(19/21)的患者疼痛症状明显缓解,CA19-9降低,HIFU治疗区域肿瘤组织明显坏死,患者生存期较对照组明显延长(P<0.05);治疗组患者未发生皮肤烧伤、胰腺炎、胃肠道穿孔等并发症。结论:HIFU能减轻晚期胰腺癌患者症状,改善生活质量,延长生存期。
Objective： To explore the effect of high intensity focused ultrasound（HIFU） therapy in the treatment of advanced pancreatic cancer and nursing methods.Methods： 36 patients were randomly divided into treatment group（n=21） and control group（n=15）.The patients were treated with type FEP-BY02 HIFU tumor therapy machine in the treatment group and the patients in the control group received supportive therapy.The treatment effectiveness and safety were observed by comparing the clinical symptoms,laboratory test results,imaging changes,complications,etc.,between the two groups.Results： The pain was obviously relieved in 90.5%（19/21） of the patients and CA19-9 decreased in the treatment group;the treated local tumor tissues were evidently necrotic and the life time was significantly longer compared with the control group（P〈0.05）.Such complications as skin burns,pancreatitis and gastrointestinal tract perforation did not occur in the treatment group.Conclusion： HIFU therapy can reduce the symptoms,improve quality of life and prolong the life time of the patients with advanced pancreatic cancer
