弹性应变率比值对乳腺肿块良恶性的诊断价值

Diagnostic value of strain ratio measurement in breast neoplasm

目的探讨弹性应变率比值对乳腺肿块诊断的临床应用价值。方法对随机检查的103例患者的109个乳腺肿块分别进行二维超声和弹性成像检查,测量肿块组织与周围组织弹性应变率比值,结果与病理对照。结果 109个肿块中,良性71个,恶性38个,良、恶性乳腺肿块弹性应变率比值分别为(2.26±1.39)和(6.95±4.08),两者差异有统计学意义(P<0.05)。二维超声、弹性应变率比值诊断恶性病变的敏感性、特异性和准确性分别为81.58%,80.28%,80.73%和86.84%,88.73%,88.07%(P>0.05);联合应用则诊断的敏感性、准确性提高至97.37%和93.58%(P<0.05)。结论以二维超声为基础,结合弹性成像技术,可提高乳腺肿块的术前诊断符合率。

Objective To explore the clinical value of strain ratio measurement with ultrasound elastography（UE） for diagnosis of breast neoplasm.Methods A total of 109 breast masses in 103 patients for diagnosis in our hospital were randomly examined with 2-dimensional ultrasonography and elastosonography.The strain ratio of the lesion and nearby breast tissue was calculated,and the results were compared with final pathological findings.Results There were 71 benign and 38 malignant lesions in the 109 breast masses.The strain ratios between benign lesion（2.26±1.39） and malignancy（6.95±4.08） were significantly different（P0.05）.The sensitivity,specificity and accuracy of 2-dimensional ultrasonography and strain ratio for breast cancer detection was 81.58%,80.28%,80.73% and 86.84%,88.73%,88.07% respectively（P0.05）.The rate of diagnostic sensitivity and accuracy was increased to 97.37% and 93.58% respectively（P0.05） by combination of 2-dimensional ultrasonography and strain ratio measurement.Conclusions Combined 2-dimensional ultrasonography with ultrasonic elastographic diagnostic method can elevate the coincidence rate of preoperative diagnosis of breast neoplasm.