儿童毛囊黏蛋白病

A case of follicular mucinosis in children

报告1例儿童毛囊黏蛋白病。患儿男,14岁。因眉间皮肤起浸润性红斑伴眉毛部分脱落半年余就诊。皮肤科检查:眉间偏左侧一约2.5 cm×3.0 cm浸润性红斑,其上覆少许片状鳞屑,皮损累及处眉毛缺失。皮损组织病理检查:表皮轻度角化不全,棘层增生,真皮毛囊上皮水肿、破坏,少许淋巴细胞移入,胶原间血管壁增厚,周围淋巴细胞及嗜酸性粒细胞浸润;阿新蓝染色示毛囊上皮内较多黏液样物质沉积。诊断:毛囊黏蛋白病。给予复方倍他米松注射液局部封闭治疗后,皮损消退。

A case of follicular mucinosis is reported. A 14-year-old boy presented with half a year history of facial pink infiltrated plaque associated with loss of hair. Histopathologic examination showed parakeratosis, acanthosis in the epidermis, there was a mild lymphocytic infiltration in the dermis around and within the affected follicles. Inflammatory lymphocytic infiltrate, admixed with several eosinophils, located around the vessels. Aleian blue stain was positive within the follicular structures. A diagnosis of follicular mu- einosis was finally made. He was successfully treated with intralesional compound betamethasone injection.