241例多部位医院感染患者的临床分析

Clinical analysis of 241 patients with multi-site nosocomial infection

目的探讨多部位医院感染的发生率、易感因素和病原学特点,以便指导临床控制。方法采用回顾性调查方式,对2006-2009年发生多部位感染241例患者进行分析。结果 241例(502例次)多部位感染患者中,下呼吸道感染最多见,占45.62%,其次为胃肠道13.35%和泌尿道8.37%;多部位医院感染病原菌中,多药耐药菌株发生率很高,占51.00%,真菌感染占33.27%;相关因素为高龄、侵入性操作和广谱抗菌药物的应用。结论多部位医院感染的发生与侵入性操作、抗菌药物不合理应用和脑血管疾病有关;规范无菌操作、合理使用抗菌药物能预防、控制多部位医院感染的发生。

OBJECTIVE To discuss the incidence rate,predisposing factors and etiological characteristics of multi-site nosocomial infection to guide the clinical control.METHODS The retrospective study was used to analyze 241 cases suffered from multi-site hospital infection during 2006-2009.RESULTS Of the 241 cases with hospital infection in multiple sites,lower respiratory tract infection was most common（45.62%）,followed by the gastrointestinal tract（13.3%） and urinary tract（8.37%）.Pathogen of multi-site nosocomial infection is in high incidence of multiple drug-resistant strains and Fungi.Correlation factors were the elderly,various invasive operations and application of broad-spectrum antibiotics.CONCLUSION Incidence rate of multi-site nosocomial infection is related to the invasive operation,abuse of antibiotics and cerebrovascular diseases.Standard aseptic technique and the rational use of antibiotics can prevent and control the multi-site hospital infection.