23例神经外科败血症诊治分析

23 cases of sepsis in neurosurgical unit:diagnosis and treatment

目的探讨神经外科败血症的临床特点及诊治。方法回顾性分析2006年1月1日-2010年1月1日医院神经外科发生的23例医院感染败血症患者临床资料。结果 2386例患者中,发生败血症23例,发生率为0.96%;23例患者中,18例患者败血症状得到了有效控制,占78.26%,在适当的抗菌药物应用后,其中60.9%在48 h内症状得到了良好控制;23例患者经治疗后,能够生活自理者6例,占26.09%,重度残疾5例,占21.74%,植物人7例,占30.43%,死亡5例,占21.74%。结论及时的诊断、敏感抗菌药物的使用是有效控制神经外科败血症的关键;该组败血症大多得到及时控制,但因原发基础疾病严重,整体愈后不良。

OBJECTIVE To search for the clinic characters and diagnosis and therapy associated with sepsis in neurosurgical unit.METHODS Clinical materials of 23 nosocomial infection patients with sepsis in neurosurgical unit from Jan 1 2006 to Jan 1 2010 were analyzed by a case retrospective analysis.RESULTS Sepsis in 18 of the 23 patients were cured（78.26%）.After appropriate antimicrobial therapy being used,the symptoms controlled within 48 hours in patients（60.9%）.Of the 23 patients,6 cases had recovery live on himself（26.09%）,5 cases with severely disabled（21.74%）,7 cases with living vegetatively（30.43%）,5 cases were died（21.74%）.CONCLUSIONS Prompt diagnosis and appropriate antimicrobial therapy being used in time are the key steps to cure sepsis in neurosurgical unit;most of cases of sepsis get the prompt control in time,but the prognosis is not good because of the serious primary diseases.