神经外科住院患者医院感染病原菌特点与耐药性分析

Clinical features of pathogens causing nosocomial infections in neurosurgery department and their drug resistance

目的探讨神经外科住院患者医院感染病原菌特点及耐药性。方法回顾性分析821例住院患者的临床资料。结果有84例发生医院感染,感染率10.2%,感染部位分布以呼吸道为主,占65.5%;共分离出86株病原菌,革兰阴性菌占68.6%,革兰阳性菌占26.7%,真菌占4.7%;分布最多的4种病原菌为大肠埃希菌、金黄色葡萄球菌、铜绿假单胞菌和肺炎克雷伯菌,分别占24.4%、19.7%、15.1%、12.8%;常见革兰阴性菌呈现出多药耐药性。结论神经外科住院患者医院感染率高,病原菌耐药性高,应加强护理和预防工作。

OBJECTIVE To investigate the pathogen features of nosocomial infection and its drug resistance in neurosurgery department.METHODS The clinical data of 821 cases from neurosurgery department were reviewed retrospectively.RESULTS The nosocomial infectious rate was 10.2%,and respiratory tract was the main infectious site（65.5%）.A total of 86 strains of pathogens were isolated with G＋（68.6%）,G-（26.7%） and fungi（4.7%）.The four main pathogens were Escherichia coli（24.4%）,Staphylococcus aureus（19.7%）,Pseudomonas aeruginosa（15.1%） and Klebsiella pneumoniae（12.8%）,and they showed multidrug resistance.CONCLUSIONS There is a high nosocomial infectious rate of inpatients in neurosurgery department,and the pathogens are drug-resistance.We should pay more attention to the management of nursing and prevention.