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uPA系统与消化系统肿瘤的研究进展 被引量:1

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摘要 肿瘤侵袭与转移是一个多因素相互依赖的多步骤的复杂过程.并需要相关的肿瘤蛋白水解酶的表达.其中一重要的蛋白水解酶就是尿激酶。
出处 《实用医学杂志》 CAS 北大核心 2011年第12期2287-2289,共3页 The Journal of Practical Medicine
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二级参考文献21

  • 1孙泽群,徐少勇,邓长生,张丽,田林.P38蛋白在大肠癌中的表达及其临床意义[J].中国肿瘤临床,2005,32(11):635-637. 被引量:11
  • 2刘宇宏,刘延香,葛繁梅,封青海,高雪梅.Pho-P38与Ki67在B细胞非霍奇金淋巴瘤中的表达及其意义[J].实用癌症杂志,2007,22(1):50-52. 被引量:2
  • 3Obata T,Brown GE,Yaffe MB.MAP kinase pathways activated by stress:the p38 MAPK pathway.Crit Care Med,2000,28 (4 Suppl):N67-77.
  • 4Husain SS,Szabo IL,Pai R,et al.MAPK (ERK2) kinase:a key target for NSAIDs-induced inhibition of gastric cancer cell proliferation and growth.Life Sci,2001,69(25/26):3045-3054.
  • 5Dass K,Ahmad A,Azmi AS,et al.Evolving role of uPA/uPAR system in human cancers.Cancer Treat Rev,2008,34 (2):122-136.
  • 6Shin BA,Yoo HG,Kim HS,et al.P38 MAPK pathway is involved in the urokinase plasminogen activator expression in human gastric SNU-638 cells.Oncol Rep,2003,10 (5):1467-1471.
  • 7Denkert C,Siegert A,Leclere A,et al.An inhibitor of stressactivated MAP-kinases reduces invasion and MMP-2 expression of malignant melanoma cells.Clin Exp Metastasis,2002,19 (1):79-85.
  • 8Kim MS,Lee EJ,Kim HR,et al.p38 kinase is a key signaling molecule for H-Ras-induced cell motility and invasive phenotype in human breast epithelial cells.Cancer Res,2003,63 (17):5454-5461.
  • 9Philipsen HP,Reichart PA,Slootweg PJ,et al.Odontogenic tumours//Barnes L,Eveson JW,Reichart PA,et al,eds.WHO classificat ion head andneck tumours.IARC Press:Lyon,2005:283-327.
  • 10Esteva FJ,Sahin AA,Smith TL,et al.Prognostic significance of phosphorylated P38 mitogen-activated protein kinase and HER-2 expression in lymph node-posi6ve breast carcinoma.Cancer,2004,100 (3):499-506.

同被引文献12

  • 1Angenete E,Langenskiold M,Palmgren I, et al. uPA and PAI-1 in rectal cancer-relationship to radiotherapy and clinical outcome [J]. J Surg Res,2009 , 153(1):46-53.
  • 2Offersen B V,Pfeiffer P,Andreasen P,et al. Urokinase plasminogen activator and plasminogen activator inhibitor type-1 in nonsmall-cell lung cancer:relation to prognosis and angiogenesis[J]. Lung Cancer, 2007,56 ( 1 ) : 43-50.
  • 3Yang MD,Lai KC,Lai TY,et aL Phenethy lisothiocyanate inhibits migration and invasion of human gastric cancer AGS cells through suppressing MAPK and NF-kappaB sig- nal pathways[J]. Anticanc er Res, 2010,30 ( 6 ) : 2135-2143.
  • 4Alfano D,Votta G,Schulze A,et al.Modulation of cellular migration and survival by c-Myc through the downregula- tion of urokinase (uPA) and uPA receptor [J]. Mol Cell Biol,2010,30(7) : 1838-1851.
  • 5Hildenbrand R, Niedergethmann M, Marx A, et al.Amplifi- cation of the urokinase-type piasminogen activator recep- tor (uPAR) gene in ductal pancreatic carcinomas identi- fies aclinically high-risk group[J]. Am J Pathol,2009,174 (6) : 2246-2253.
  • 6Halamkova J, Kiss I,Pavlovsky Z, et al. Clinical rele- vance of uPA,uPAR,PAI 1 and PAI 2 tissue expression and plasma PAI 1 level in colorectal carcinoma patients [J]. Hepatogastroenterology, 2011,58(112): 1918-1925.
  • 7Langenskitild M,Holmdahl L,Angenete E,et al. Differ- ential prognostic impact of uPA and PAI-1 in colon and rectal cancer[J]. Tumour Biol, 2009,30(4):210-220.
  • 8李竹林,朱明才,董蒲江.结肠癌中VEGF-D和uPA的表达与侵袭转移的关系[J].第三军医大学学报,2008,30(22):2146-2149. 被引量:11
  • 9历春,盖晓东,刘晓红.COX-2,MMP-9和bFGF在大肠癌中的表达及临床意义[J].北华大学学报(自然科学版),2009,10(1):46-49. 被引量:6
  • 10雒洪志,黄宗海,余元龙,陈宏,周仕海,邓庆炎.MMP-9在结肠癌中的表达及其临床意义[J].肿瘤学杂志,2009,15(6):552-555. 被引量:11

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