期刊文献+

低度恶性子宫内膜间质肉瘤13例临床病理分析

下载PDF
导出
摘要 目的探讨低度恶性子宫内膜间质肉瘤(LESS)的临床病理学特征及其诊断和鉴别诊断。方法对13例LESS患者的肿瘤组织标本行常规HE染色及免疫组化标记,分析其临床及病理学特征。结果 HE光镜下,13例LESS均显示子宫内膜间质细胞呈弥漫性增生,并呈浸润性生长,平滑肌组织间隙内可见瘤组织灶状分布,子宫内膜螺旋小动脉血管清晰可见,其中5例伴不同程度的平滑肌分化。免疫组化显示,13例标本中肿瘤细胞的CD10及V im en-tin均强烈表达,PR阳性者9例,ER阳性者10例,SMA阳性者4例,CD34和Desm in均阴性。结论 LESS具有多向分化特点,因其组织形态多变,需结合组织病理形态、免疫组化染色和临床资料对其进行诊断及鉴别。
出处 《现代中西医结合杂志》 CAS 2011年第18期2255-2256,共2页 Modern Journal of Integrated Traditional Chinese and Western Medicine
  • 相关文献

参考文献8

二级参考文献30

  • 1黄志勇,实用妇产科病理学,1996年,155页
  • 2Yokoyama Y,Ono Y,Sakamoto T,et al. Asymptomatic intracardiac metastasis from a low-grade endometrial stromal sarcoma with successful surgical resection[J]. Gynecol Oncol,2004,92(3):999-1001.
  • 3Leunen K,Amant F,Debiec-Rychter M,et al. Endometrial stromal sarcoma presenting as postpartum haemorrhage: report of a case with a sole t(10;17)(q22;p13) translocation[J]. Gynecol Oncol,2003,91(1):265-71.
  • 4Gunawan B,Schulten HJ,Fuzesi L. Identification of a BAC clone overlapping the t(6p12.3) breakpoint in the cell line ESS-1 derived from an endometrial stromal sarcoma[J]. Cancer Genet Cytogenet,2003,147(1):84-6.
  • 5Leath CA,Straughn JM,Conner MG,et al. Immunohistochemical evalulation of the c-kit proto-oncogene in sarcomas of the uterus: a case series[J]. J Reprod Med,2004,49(2):71-5.
  • 6Longacre TA,Hendrickson MR,Kapp DS,et al. Lymphangioleiomyomatosis of the uterus simulating high-stage endometrial stromal sarcoma[J]. Gynecol Oncol,1996,63(3): 404-10.
  • 7Matsuura Y,Yasunaga K,Kuroki H,et al. Low-grade endometrial stromal sarcoma recurring with multiple bone and lung metastases: report of a case[J]. Gynecol Oncol,2004,92(3):995-8.
  • 8Mourra N,Tiret E,Parc Y, et al. Endometrial stromal sarcoma of the rectosigmoid colon arising in extragonadal endometriosis and revealed by portal vein thrombosis[J].Arch Pathol Lab Med,2001,125(8):1088-1090.
  • 9Bosincu L, Massarelli G, Cossu Rocca P, et al. Rectal endometrial stromal sarcoma arising in endometriosis: report of a case [J]. Dis Colon Rectum, 2001,44(6):890- 892.
  • 10Chang YC, Wang TY, Tzen CY. Endometrial stromal sarcoma of the vagina[J]. Zhonghua Yi Xue Za Zhi (Taipei), 2000, 63 (9): 714 -719.

共引文献80

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部