摘要
２８ 例急性颅脑损伤以 Ｇ Ｃ Ｓ评分分组， Ａ 组 Ｇ Ｃ Ｓ≤８ 分， Ｂ 组 Ｇ Ｃ Ｓ＞ ８ 分，结果显示，脑脊液及血清 Ｉ Ｌ－ ６均在伤后第１ 天达峰值，其中脑脊液 Ｉ Ｌ－ ６ 两组峰值无显著差异，血清 Ｉ Ｌ－ ６ 两组差异显著，且其下降速度亦有显著差异。说明颅脑损伤后 Ｉ Ｌ－ ６ 主要由 Ｃ Ｎ Ｓ产生，且血清 Ｉ Ｌ－ ６ 水平与临床病情和炎症反应变化呈平行关系， Ｉ Ｌ－ ６ 可作为判定机体免疫状态和临床判定疗效和预后指标之一。
Purpose To determine the level of cerebrospinal fluid and IL-6 in serum in brain-injured patients and the correlation between this level and the clinical course of recovery from head injury. In this study, 28 patients were divided into 2 groups. In group A GCS is ≤8, and in group B GCS>8. The highest peaks of IL-6 in CSF and serum were all found on the first day after injury. These was no significant difference in peak values of IL-6 in CSF between these 2 groups and these was sigificant difference in serum. Conclusion IL-6 comes from CNS after brain injury and the IL-6 level in serum is correlated with the clinical course of recovery and the inflammatory reaction. IL-6 can be used as an index in evaluation of immune state and prognosis.
出处
《苏州医学院学报》
1999年第8期868-869,共2页
Acta Academiae Medicinae Suzhou
