1Bokemeyer C,Bondarenko J,Makhson A,et al.Fluorouracil,leucovo- fin,and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer [J].J Clin Oncol,2009,27 (5):663-671.
3Levi F, Misset JL, Brienza S, et al. A chronopharmacologic paase clinical trial with 5 -fluorouracil, folinic acid, and oxaliplatin using an ambulatory multi - channel programmable pum. High omtitumor effective- sess againse metastatic colorectal cancer [ J ]. Cancer, 1992, 69 (4) : 893.