ICU患者下呼吸道感染的细菌分布和耐药性分析

ICU patients with lower respiratory tract infections and antimicrobial resistance of bacterial distribution

目的探讨ICU患者下呼吸道感染细菌分布特征及耐药性分析。方法收集我院2008年10月至2010年10月间ICU病房患者240例痰液标本进行菌株鉴定和药敏实验。结果 240例患者痰液标本分离出病原菌210例,阳性率占75%。其中革兰阴性杆菌占70%,革兰阴性球菌占21%,真菌占9%,以铜绿假单胞菌居首位,其次为金黄色葡萄球菌,肺炎克雷伯氏菌,不动杆菌属和真菌。结论革兰阴性杆菌为ICU病房患者医院感染主要病原菌,对常用抗菌药呈高度耐药特征,并有上升趋势。根据细菌培养及药物敏感实验合理选用抗菌药物,是防止抗菌素滥用,控制院内感染病原传播的关键。

Objective To investigate the ICU patients with lower respiratory tract infections and drug resistance distribution Methods From hospital from October 2008 to October 2010,240 patients between the ICU wards isolates were identified in sputum specimens and susceptibility testing Results 240 patients with pathogens isolated from sputum of 210 patients,the positive rate of 75% Which accounted for 70% of Gram negative bacteria,Gram negative bacteria accounted for 21%,9% of fungi.Pseudomonas aeruginosa ranked first,followed by Staphylococcus aureus,Klebsiella pneumoniae,Acinetobacter genus and fungi Conclusion ICU ward Gram negative bacilli are the main pathogens of nosocomial infection,and is highly resistant to antibiotic characteristics,and on the rise Based on bacterial culture and drug sensitivity tests rational use of antimicrobial drugs to prevent the abuse of antibiotics to control the spread of key pathogens of nosocomial infections.