骨质疏松症治疗药物的研究进展

Research Progress in Therapeutic Drugs against Osteoporosis

骨质疏松症是以骨量减少、骨的微观结构退化为特征,致使骨的脆性增加并易于发生骨折的一种全身性骨骼疾病,是当前严重危害人类特别是绝经妇女和老人的疾病之一。近年来出现了许多预防和治疗骨质疏松症的药物,极大地推动了骨质疏松症理论基础的完善和临床治疗研究。就该领域的研究进展进行了简要综述。

Osteoporosis is a general bone disease characterized by low bone mass and microarchitectural deterioration of bone tissue, which lead to bone fragility and a consequent susceptibility to fracture. It is one of serious diseases, which endangers health of humans, particularly postmenopausal women and old men. In recent years, a lot of drugs have been developed for prevention and treatment of osteoporosis and also largely promote development of clinical research and theoretics of osteoporosis. This article summarizes the overall development in therapeutic drugs against osteoporosis.