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上皮细胞钙粘蛋白和β-连环蛋白在恶性胸腔积液中的诊断价值 被引量：1

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摘要 目的通过检测胸腔积液中上皮细胞钙粘蛋白(E-cadherin)和β-连环蛋白(β-catenin)的含量,探讨其在恶性胸腔积液中的诊断价值。方法收集65例临床上已确诊患者的胸腔积液标本,分为恶性(33例)和结核性胸腔积液(32例)2组,采用酶联免疫吸附法(ELISA)检测E-cadherin和β-catenin的含量。结果结核性胸腔积液E-cadherin水平为(7.38±0.51)ng/L,恶性胸腔积液水平为(9.78±1.83)ng/L。结核性胸腔积液β-catenin水平为(0.68±0.11)ng/L,恶性胸腔积液水平为(1.78±1.13)ng/L。恶性胸腔积液E-cadherin和β-catenin水平明显高于结核性胸腔积液(P<0.05),相关分析表明E-cadherin和β-catenin的表达具有正相关性(P<0.01,r=0.478)。结论 E-cadherin和β-catenin与肿瘤的浸润和转移有关,恶性胸腔积液中两者的水平显著增高。E-cadherin和β-catenin对结核性和恶性胸腔积液的诊断有一定价值。
作者 朱早君 邵桂敏
机构地区 安阳钢铁集团公司职工总医院呼吸内科 郑州澍青医学专科学校内科教研室
出处 《中国医学工程》 2011年第4期115-116,共2页 China Medical Engineering
关键词 恶性胸腔积液 上皮细胞钙粘蛋白 Β-连环蛋白
分类号 R561 [医药卫生—呼吸系统]
  • 相关文献

参考文献7

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共引文献5

同被引文献8

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中国医学工程
2011年 第4期

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