事关心病

The Heart of the Matter

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摘要对于冠状动脉出现问题，快速与准确地诊断心脏病并分析损伤程度极其重要。而成熟的小RNA在血清中大量存在、容易测量，并且保持稳定的水平。如果发现小RNA对疾病发展有指示作用，

作者 Terry S.Elton 刘磊

出处《生物技术世界》 2011年第3期8-15,共8页 Biotech World

关键词小RNA 冠状动脉损伤程度指示作用心脏病血清成熟

参考文献7

1T.Adachi et al."Plasma microRNA 499 as a biomarker of acute myocardial infarction,". Clinical Chemistry . 2010
2M.F.Corsten et al."Circulating MicroRNA-208b and MicroRNA-499 reflect myocardial damage in cardiovascular disease,". Circ Cardiovasc Genet . 2010
3K.Wang et al."Export of microRNAs and microRNA—protective protein by mammalian cells,". Nucleic Acids Research . 2010
4T.S.Chen et al."Mesenchymal stem cell secretes microparticles enriched in pre—microRNAs,". Nucleic Acids Research . 2010
5C.Yin et al."A novel role of microRNA in late preconditioning: upregulation of endothelial nitric oxide synthase and heat shock protein 70,". Circulation Research . 2009
6A.Care et al."MicroRNA-133 controls cardiac hypertrophy,". Nature Medicine . 2007
7Ji R,Cheng Y,Yue J,et al.MicroRNAs are aberrantly expressed in hypertrophic heart:do they play a role in cardiac hypertrophy?. Anterican Journal of Pathology . 2007

生物技术世界

2011年第3期

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