100例经阴道B超引导下卵巢穿刺电凝治疗多囊卵巢综合征的疗效观察

Observation on the curative effect of transvaginal B ultrasound guided ovarian puncture and electrocoagulation in treatment of 100 cases with polycystic ovary syndrome

目的:分析经阴道B超引导下卵巢穿刺电凝治疗多囊卵巢综合征(PCOS)的疗效。方法:对100例PCOS经药物治疗无效的患者,经阴道B超引导下对未成熟卵泡进行穿刺,并电凝打孔,观察术前、术后黄体生成素(LH)、卵泡刺激素(FSH)、睾酮(T)、雌二醇(E2)变化,术后月经恢复、排卵及妊娠情况。结果:100例患者中98例术后月经明显改善,术后LH、LH/FSH、T、E2值均较术前降低,FSH值明显升高,术前、术后有明显差异,术后排卵率为76.0%,妊娠率为55.0%。结论:经阴道B超引导下穿刺电凝未成熟卵泡,可以改善PCOS患者激素紊乱状态,恢复月经,提高妊娠率,损伤小,是药物治疗失败的有效治疗方法之一。

Objective：To analyze the curative effect of transvaginal B ultrasound guided ovarian puncture and electrocoagulation in treatment of polycystic ovary syndrome（PCOS）.Methods：100 patients with PCOS who were not responsive to drug treatment received transvaginal B ultrasound guided ovarian puncture of immature follicles and drilling by electrocoagulation,the changes of luteinizing hormone（LH）,follicle stimulating hormone（FSH）,testosterone（T） and estradiol levels before and after operation,the recovery of menstruation,ovulation and pregnancy after operation were observed.Results：Among 100 patients,the menstruation situations of 98 patients were improved significantly,the levels of LH,LH/FSH,T and estradiol after operation were significantly lower than those before operation,while the FSH level increased,there was significant difference before and after operation;after operation,the ovulation rate was 76.00%,and the pregnancy rate was 55.00%.Conclusion：Transvaginal B ultrasound guided ovarian puncture and electrocoagulation of immature follicles can improve hormonal disorder,recover menstruation,increase pregnancy rate and reduce injury,which is an effective method for the patients who are not responsive to drug treatment.