芪桂消症颗粒对血瘀模型大鼠血液黏度的影响

The Effect of Qi-gui Xiao-zheng Granule on Blood Viscosity in Animal Model of Blood Stasis

目的:探索芪桂消症颗粒活血化瘀的作用机理。方法:用高分子右旋糖酐尾静脉注射建立大鼠血瘀模型,观察芪桂消症颗粒对血瘀模型大鼠全血黏度、血浆黏度的影响。结果:芪桂消症颗粒能显著降低大鼠血瘀模型的全血黏度和血浆黏度、红细胞压积及红细胞刚性指数。结论:芪桂消症颗粒有改善血瘀动物模型血液高黏度状态的作用。

Objective：To investigate the mechanism of action of Qi-gui Xiao-zheng Granule on promoting blood flow to dissolve blood stasis. Method：The blood stasis models of rats were made by intravenous injection of Giant Mmolecule Dextran in vena caudalis. Then the effect of Qi-gui Xiao-zheng Granule was observed on whole blood viscosity and blood plasm viscosity in the blood stasis model of rat. Result：Qi-gui Xiao-zheng Granule could cut down whole blood viscosity,blood plasm viscosity, HCT, and erythrocyte rigidity index in the blood stasis model of rat. Conclusion ： Qi-gui Xiao-zheng Granule has the effect of improving blood viscosity in the animal model of blood stasis.