N末端脑钠肽前体评价慢性心力衰竭患者心脏康复治疗效果

The effect of cardiac rehabilitation in patients with chronic heart failure evaluated by NT-proBNP

目的通过观察N末端脑钠肽前体(NT-proBNP)水平,评价慢性心力衰竭患者在常规治疗基础上进行心脏康复与单纯使用药物治疗的效果差异。方法 70例慢性心力衰竭患者在常规药物治疗心衰基础上,随机平分为两组:A组(药物+心脏康复组)和B组(单纯药物治疗组),通过规则治疗12个月后复查NT-proBN水平和对比再住院率。结果治疗后,A组所测得NT-proBNP数值对比B组所测得NT-proBNP数值明显下降,差异有明显统计学意义(P<0.05);A组患者因心衰再住院率亦比B组低。结论在常规心衰治疗基础上,进行安全的心脏康复治疗比单纯使用药物治疗更加能改善慢性心力衰竭患者心功能。

Objective To evaluate the effectiveness of drug treatment suplemented with cardiac rehabilitation in comparison with drug treatment alone by observation on levels of NT-proBNP.Methods Based on conventional treatment for heart failure,patients were divided into two groups： group A（drug treatment combined with cardiac rehabilitation） and group B（only drug treatment）.Levels of NT-proBNP and readmission rates of patients were compared berween these two groups after a therapeutic course of 12 months.Results The level of NT-proBNP in patients of group A was significantly lower than that of patients in group B,and the readmission rate of patients in group A was significantly lower than that of patients in group B（P0.05）.Conclusion Drugs supplemented with cardiac rehabilitation can significantly improve the heart function of patients with chronic heart failure,and it is much superior to the application of simple drug therapy.