盐酸左旋布比卡因在臂丛神经阻滞麻醉中的应用

The application of levobupivacaine in the brachial plexus blockage

目的探讨盐酸左旋布比卡因在臂丛麻醉中的效果。方法选取60例拟行上肢和肩部手术的病人,随机分为盐酸左旋布比卡因组(LBUP)和盐酸布比卡因组(BUP)(对照组),每组各30例,采用臂丛麻醉方法观察一般生命体征,起效时间、完全阻滞时间、持续时间及镇痛效果和不良反应。结果三种入路臂丛麻醉下两组病人HR、BP、SpO2无明显差异(P>0.05),起效时间、完全阻滞时间和镇痛效果、不良反应无明显差异(P>0.05),LBUP组恢复时间比BUP长。结论 LBUP麻醉效果确切,作用时间长,毒性反应小,适合在临床推广使用。

Objective To research the therapeutic efficacy and side effects of levobupivacaine in the use of brachial plexus blockage.Methods 60 patients receiving upper limb and shoulder operations were randomly divided into to group levobupivacaine（LBUP,n=30）and group bupivacaine（BUP,n=30）.The brachial plexus block was used.The vital sign,onset times of sensory block and complete sensory block,block duration,analgesia quality and side effects were documented.Results Statistical differences in HR、BP、SpO2 between both groups with three approaches were not observed.The onset times for sensory block and complete sensory block were not statistically different between the groups（P〉0.05）.But the block duration of sensory nerve of group LBUP was significantly longer than that group BUP（P〈0.05）.Conclusions The levobupivacaine provides comfortable anesthesia and analgesia,and longer block duration of nerver with less toxicity in Brachial plexus block.It is worth of using widely in clinical practice.