摘要
系统性红斑狼疮(systemic lupus erythematosus,SLE)是一种累及多系统、多器官并有多种自身抗体出现的自身免疫性疾病。多数SLE患者存在抑郁情绪。抑郁与患者的疾病活动、累积损害、激素用量以及抗核糖体P蛋白抗体(anti-ribosomal P protein antibodies,anti-P)之间的相关性研究结果各不相同;抑郁与患者的睡眠质量、疲乏症状、纤维肌痛和偏头痛、认知功能、焦虑以及治疗依从性均有关联。
Systemic lupus erythematosus(SLE) is a chronic autoimmune disease characterized by a diverse array of autoantibody production that affects multiple systems and organs.Most of patients are in depression mood.The relationship between depression and disease activity,cumulative damage,dosage of glucocorticoid and anti-ribosomal P protein antibodies(anti-P) were still controversial.Depression was correlated with sleep quality,fatigue,fibromyalgia,migraine,cognitive impairment,anxiety and patients' medication compliance.
出处
《中华疾病控制杂志》
CAS
2011年第6期519-523,共5页
Chinese Journal of Disease Control & Prevention
基金
国家自然科学基金重点项目(30830089)
关键词
红斑狼疮
系统性
抑郁
危险因素
Lupus erythematosus
systemic
Depression
Risk factors