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miRNA与卵巢癌的研究进展 被引量：1

Advances in research of miRNA and ovarian cancer
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摘要 微小RNA（micro-RNA，即miRNA）是长约21-23nt的非编码短链RNA，是基因表达的转录后调节因子，通过与靶miRNA特异的碱基配对，引起靶miRNA降解或翻译抑制。近年研究表明miRNA在肿瘤的发生和发展中起着重要作用。 MicroRNA （miRNA） constitute a large family of smaU,approximately 21 to 23 nucleotide-long, non-coding RNA that is a key post-transcriptional regulators of gene expression,By base pairing to mRNA, miRNA mediate translational repression or miRNA degradation. The recent study find that miRNA play an important role in carcinogenesis. Here is a reviews of the research advances of miRNA and ovarian cancer.
作者 高金瑜(综述) 李长华(审校)
机构地区 南京医科大学附属淮安一院妇科
出处 《肿瘤研究与临床》 CAS 2011年第5期354-356,共3页 Cancer Research and Clinic
关键词 MIRNA 卵巢肿瘤 基因表达调控 microRNAs Ovarian neoplasms Gene expression regulation
分类号 R394 [医药卫生—医学遗传学]
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参考文献31

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同被引文献34

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肿瘤研究与临床
2011年 第5期

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