中等负荷运动对心理应激大鼠ACTH、T淋巴细胞亚群的影响

Influence of Medium-Sized Load Exercise on Mouse ACTH of Psychological Stress and T-lymphocyte

应激对免疫功能的影响是复杂的,机体往往因应激源的种类、刺激强度、持续时间、被测个体差异等不同而产生不同的免疫应答。在应激状态下,中枢神经系统、内分泌神经系统的异常变化是影响机体免疫功能的主要中介。身体锻炼作为一种有效的心理干预手段,可以通过多种途径降低心理应激反应。本研究试图采用免疫学、神经内分泌学手段,通过对促肾上腺皮质激素和T淋巴细胞亚群的检测,探讨中等负荷身体锻炼应对心理应激的免疫学机制。

Influence of stress on immune function is complicated.Organism,according to the sources of psychological stress,the stimulus intensity,the time of duration and the different immune responds of examined individuals etc.,often produces different immunity replies.Under the psychological stress state,unusual change of central nervous system and neuroendocrine system is the main intermediary which influences the function of organism immune.As an effective method of psychological intervenes,body exercises can reduce psychological stress through multiple channels.Adopting the approaches of immunology and endocrinology and getting through the detection of ACTH and T-lymphocyte subsets,this paper attempts to study the immunology mechanisms of moderate exercise replying the psychological stress.