颈动脉脉搏波速度与高血压患者动脉功能的关系研究

Relation of carotid pulse wave velocity and carotid artery function

目的:探讨原发性高血压患者颈动脉脉搏波速度(carotid pulse wave velocity,CPWV)与颈动脉功能变化的关系。方法:对60例高血压患者(实验组)和56例健康人士(对照组)采用组织多普勒显像(TDI)技术检测右颈总动脉,根据同步心电图描记,对电-机械时间、脉搏波时间进行测量,对颈动脉脉搏波速度进行计算。结果:颈动脉脉搏波速度实验组为(2.8±1.1)m/s,对照组为(0.9±0.6)m/s,两组比较差异有统计学意义(t=11.255,P<0.001);脉压实验组(62.6±16.4)mmHg,对照组(38.5±10.4)mmHg,差异有统计学意义(t=8.658,P<0.001)。结论:颈动脉脉搏波速度与脉压之间有很密切的关系,可以在临床上把其作为高血压病动脉功能的评价标准。

Objective： To explore the relation of carotid pulse wave velocity（CPWV） and carotid artery function.Methods： The right common carotid artery was detected by tissue Doppler imaging.Based on synchronized electrocardiography,electromechanical time and pulse wave time were measured,and CPWV was calculated.Results： The CPWV was（2.8±1.1）m/s in experimental group,and（0.9±0.6） m/s in control group.There was significant difference between two groups（t=11.255,P0.001）.The pulse pressure was（62.6±16.4）mmHg in experimental group,and（38.5±10.4）mmHg in control group with significant difference between them（t=8.658,P0.001）.Conclusions： CPWV is close related with pulse pressure,and can be criteria for evaluation of arterial function in patients with hypertension.