短暂性脑缺血发作患者血脂水平与ABCD2评分的相关性研究

Relationship Between Lipids and ABCD2 Score in Patients with Transient Ischemic Attack

目的:探讨短暂性脑缺血发作(transient ischemia attach,TIA)患者血脂水平对预后的影响及其临床意义。方法:回顾性分析以2009年最新定义为诊断标准的我院TIA患者62例,根据ABCD2评分进行危险分级。其中,低危组(0～3分)患者16例、中危组(4～5分)患者20例,高危组(6～7分)患者26例,比较三组患者血脂水平的差异及其预后效果的影响。结果:三组患者中血脂水平从高到低依次为:高危组、中危组与低危组,其中高危组血脂水平与其它两组患者血脂水平的差异均有统计学意义(P<0.05),但中危组与低危组间差异无统计学意义(P>0.05)。低、中危组患者血脂平均水平随ABCD2分值增高呈轻度上升趋势,高危组患者血脂平均水平随ABCD2分值明显增高。血脂水平越高其预后效果相对越差。结论:血脂水平与TIA患者ABCD2评分呈正相关的趋势,而与预后效果呈负相关的趋势。

Objective： To study the effect of lipid levels on the prognosis of patients with transient ischemia attack （TIA） and its clinical significance. Methods： According to the latest definition of TIA in 2009 as inclusion criteria, 62 patients were diagnosed as TIA in our hospital. Their indicators were retrospectively analyzed and patients were divided according to their ABCD2 score into three groups： 16 cases in low risk group （0 to 3 points）, 20 cases in mid risk group （4 to 5 minutes）, and 26 cases in high risk group （6 to 7 points）. Difference of lipid levels and prognosis effect were compared between the three groups. Results： The sequence of groups accord- ing to the lipid levels from high to low were high risk group, mid risk group, and low risk group. The difference of lipid levels between the high risk group and the other two groups were statistically significant （P 〈0.05）, but there was no significant difference between low risk group and mid risk group. As the ABCD2 score increases, the lipid levels rose slightly in the low risk and mid risk group, but rose greatly in the high risk group. The higher the lipid level was, the worse the prognosis effect it made. Conclusion： There was positive correlation between Lipids levels and ABCD2 score, but a negative correlation between the Lipids levels and its prognosis effect.