冠状动脉内多普勒超声研究冠状动脉血流速度

The Value of Doppler Guidewire for Intravascular Measurement of Coronary Artery Flow Velocity

目的:评价冠状动脉内多普勒超声测量冠脉血流速度的应用价值。材料和方法:利用冠状动脉内多普勒血流钢丝(FloWire) 测量21 例冠状动脉狭窄患者和12 例正常冠状动脉的血流速度。结果:左前降支冠脉狭窄远端的平均最大血流速度(APV) 、舒张期最大血流速度(DPV) 和舒张期与收缩期流速比值(DSVR) 均显著低于正常组测值。结论:应用冠脉内多普勒超声技术可评价正常和冠脉狭窄病变患者的冠脉血流速度,这为定量研究冠脉血流动力学提供了新方法。

Purpose: This study was to assess the clinical application potential of the Doppler FloWire. Meterials and Methods: Doppler FloWire was used for measurement of coronary flow velocity in 12 angiographically normal coronary arteries (CA) and in 21 segments distal to significantly stenosed arteries of left anterior descending branch. Results: The average peak velocity, diastolic peak velocity and diastolic to systolic peak velocity ratio in stenosed CA were significantly lower than those of normal arteries (P<0.05). Conclusion: Doppler Flo Wire can be used for intravascular measurement of hemodynamic changes in coronary artery. The measurement of coronary artery flow velocity is considerably useful for assessing the severity of coronary artery stenosis.