中药保肝康抗CCl_4慢性肝损伤的实验研究

COUNTERACTIVE EFFECT OF BAO GAN KANG ON CHRONIC HEPATIC TNJURY INDUCED BY CCL4

目的：研究中药保肝康抗慢性肝损伤的作用及机理。方法：采用ＣＣｌ４ 复制慢性肝损伤动物模型，设甘草甜素为对照药物。结果：保肝康具有改善肝功的作用，并可以改善肝组织病理；在对慢性肝损伤减轻脂肪变性、阻止肝纤维化方面均优于甘草甜素。

Objective:To study counteractive effect of Bao Gan Kang(BGK)on chronic hepatic injury.Methhods:Chronic hepatic injury animal model induced by CCl 4 was applied to the research,and glycyrrhizin served as control druy.Results:BGK had the effect of improving liver functions and pathologic change of hepatic tissue.It was superior to glycyrrhizin in abating fatty degeneration of liver and resisting liver fibrosis.Conclusion:To resist lipid peroxidation is the important mechanism of BGK resisting chronic hepatic injury.