男性不育症患者637例支原体感染及其药物敏感性分析

Investigation on Mycoplasma infection and its drug sensitivity for 637 male patients with infertility

目的了解男性不育症患者支原体感染及其耐药情况,为男性不育症诊治和控制支原体感染提供依据。方法对637例男性不育症患者的精液进行解脲支原体(Uu)和人型支原体(Mh)分离,并检测其对12种常用抗生素的敏感性。结果支原体的总感染率51.49%,Uu,Mh,Uu+Mh的感染率分别为27.63%、2.98%和20.88%,12种抗生素对支原体(Uu,Mh,Uu+Mh)敏感性和耐药各不相同。结论男性不育症患者中有着较高的支原体感染率,临床上对不育男性常规开展支原体培养及药敏检测很有必要。

Objective To investigate the status of the Mycoplasma infection of the male patients with infertility and the drug resistance of Mycoplasma to antibiotics.Methods The Mycoplasma urealytium（Uu） and Mycoplasma hominis（Mh） in semen samples from 637 infertile men were isolated and assayed for drug sensitivity with 12 antibiotics.Results The infection rate of total Mycoplasma in the infertile males＇ semen was 51.49%,while that of Uu,Mh,Uu＋Mh were 27.63%,2.98% and 20.88% respectively.The drug sensitivity and resistance of Mycoplasma towards 12 antibiotics differed respectively.Conclusions The semen of infertile male patients have high infection rate of Mycoplasma.It is necessary to make Mycoplasma culture and drug sensitivity test as routine methods for male patients with infertility.