洛美沙星注射剂治疗细菌性感染的临床疗效

Clinical effect of pulverous lomefloxacin injection in treatment of bacterial infections

目的:评价国产洛美沙星抗细菌性感染的临床疗效.方法:120例呼吸道、泌尿道和肠道的细菌性感染病例随机分成两组,分别用冻干粉盐酸洛美沙星和乳酸环丙沙星治疗.另一开放组43例仅用洛美沙星治疗.结果:洛美沙星随机治疗组和开放组总有效率88.3%和83.7%,而环丙沙星治疗组为90.0%.两组之间有效率和细菌的清除率的差异均无显著性差异(P>0.05).结论:冻干粉盐酸洛美沙星注射剂疗效及不良反应与乳酸环丙沙星相当.

AIM : To evaluate the clinical efficacy of domestic lomefloxacin injection in treating various bacterial infection. METHODS: A randomized control study was conducted on 120 patients with respiratory, urinary and intestinal infections. They were equally divided to receieve lomefloxacin and ciprofloxacin respectively. In the other group, 43 patients with bacterial infections were only treated by lomefloxacin. The rate of clinical efficacy, and rateof bacterial elimination were observed. RESULTS: In the lomefloxacin randomized group and other group the efficacy rates were 88. 3% and 83. 7% respectively, as compared with 90. 0% in ciprofloxacin group. There were no significant statistic differences between the 2 drugs for the clinical efficacy and bacterial eradication rate. CONCLUSION: The eifficacy and safety of 2 drugs were similar.