一起成人风疹疫情的流行病学调查

Epidemiological Investigation of a Rubella Prevalence among Adults in Shandong Province of China

目的对一起经实验室确诊的、以成人为主的风疹疫情进行流行病学调查,探讨风疹疫情发生原因。方法对2006年1～6月发生在山东省邹平县某企业的一起成人风疹疫情,用酶联免疫吸附试验检测风疹IgM抗体以明确诊断,并开展流行病学调查。结果该起疫情共报告风疹318例,该县罹患率44.15/10万;病例主要集中在该企业园区内,发病217例,园区罹患率为310.06/10万;发病年龄主要集中在16～28岁,占74.53%(237/318),6～15岁占25.47%(81/318);男、女性别比为1.43∶1(187∶131)。采集145例血清标本,检测风疹和麻疹抗体,风疹IgM阳性82例,阳性率56.55%,麻疹IgM均阴性。结论该起风疹疫情具有典型的成人流行病学特征,外来流动人口中易感人群聚集和其他内外环境等流行因素的协同作用,是该起风疹疫情的主要原因。

Objective To investigate the reasons of rubella prevalence confirmed by laboratory among adults in a large factory in Zouping county, Binzhou prefecture of Shandong from January to June in 2006. Methods IgM antibody were tested by ELISA for early stage diagnosis. Results Total 318 rubella cases were reported with 44.15 per hundred thousands population （311/720261）of the incidence rate in the county, 217 cases were reported in this factory, the incidence rate of this factory was 310.06 per hundred thousands population. Most cases（74.53%）occurred among adults between 16 and 28 years old, and the cases from 6 to 15 years old were 25.47%. Male were much more than female with 1.43：1（187：131）of the gender ratio. 145 sera specimen were collected with 56.55%（82/145）positive rate of rubella IgM and measles IgM negative of all. Conclusion This rubella epidemic was of a typical epidemiology features among adult. Gathering of susceptible migrant population and environmental factors in this factory are the main reason of the Rubella prevalence.