摘要
以氯化苄为原料,经混酸硝化、超声波辐射相转移催化水解及超声波辐射Pd/C催化氢转移还原等3步反应合成了标题化合物。通过改进生产工艺,总收率可达64.8%。产物的结构经IR、1HNMR、MS及元素分析得以表征。
4-Aminobenzyl alcohol was synthesized with overall yield of 64.8% by nitration,hydrolyzation with phase transfer catalytic method under ultrasonic irradiation and catalytic transfer hydrogenation with Pd/C in the presence of ammonium formate under ultrasonic irradiation.The products were characterized by IR,1HNMR,MS and elemental analysis.
出处
《化学试剂》
CAS
CSCD
北大核心
2011年第6期564-566,共3页
Chemical Reagents
基金
国家自然科学基金资助项目(51074069)
湖南省自然科学基金资助项目(07JJ6068)
湖南省科技计划资助项目(2010GK3161)
关键词
对氨基苯甲醇
超声波辐射
相转移催化剂
苄氯
转移加氢
4-aminobenzyl alcohol
ultrasonic radiation
phase transfer catalyst
benzyl chloride
transfer hydrogenation
