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联合检测抗CCP与RF在类风湿关节炎诊断中的临床价值 被引量:4

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摘要 目的探讨抗环瓜氨酸肽抗体(抗CCP)与类风湿因子(RF)联合检测在类风湿性关节炎(RA)中的诊断价值。方法对96例RA早期疑似患者和81例患病2年以上的RA患者,采用酶联免疫吸附法(ELISA)定量检测抗CCP,采用免疫散射比浊法定量检测RF,并对检测结果进行评价分析。结果抗CCP抗体、RF及联合检测结果在早期疑似RA患者中的阳性率分别为46.01%、55.21%和69.94%;在患病2年以上RA患者中的阳性率分别为46.27%、53.73%、73.13%。抗CCP和RF联合检测与各自单项检测结果在两组患者中分别比较,差异均有统计学意义(P<0.05)。结论抗CCP和RF联合检测可提高类风湿性关节炎的诊断率,在早期类风湿关节炎诊断中的临床意义重大。
作者 李艳霞
出处 《中国医药指南》 2011年第17期78-79,共2页 Guide of China Medicine
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