化痰开窍中药结合西药治疗重型脑室出血21例疗效观察

Observation on curative effects of traditional Chinese m edicine of Huatan Kaiqiao(化痰开窍 ) combined with western medicine on 2 1patients with severe intraventricular hemorrhage

目的 :观察化痰开窍中药结合西药治疗重型脑室出血的临床疗效。方法 :4 2例重型脑室出血患者随机分为中西药组和西药组各 2 1例。 2组均采用常规西药治疗 ,中西药组另外加用安宫牛黄丸、醒脑静注射液及化痰开窍汤药。每日评定神经功能缺损程度 1次 ,观察时间 4 5日。结果 :中西药组总有效率 76.2 % ,西药组总有效率 4 7.6% ,2组比较有显著性差异 ( P<0 .0 5 )。中西药组起效时间平均为 ( 6.94± 1.0 0 )日 ,短于西药组〔( 8.2 0± 1.73 )日 ,P<0 .0 5〕。结论 :中西药结合治疗重型脑室出血疗效较单纯西药好 ,其机制可能在于减轻脑水肿 。

Objective:To observe the clinically curative effects of Huatan Kaiqiao( HTKQ,化痰开窍 ) herbs combined with western medicine( WM) on severe intraventricular hemorrhage( SIH) .Methods:4 2 patients with SIH were randomly divided into traditional Chinese medicine and western m edicine( TCM WM) group( n=2 1) and WM group( n=2 1) .The conventional treatments with WM were used to both two groups while in TCM WM group the Angong Niuhuang Pill(安宫牛黄丸 ) ,the Xingnaojing Injection(醒脑静注射液 ) and HTKQ herbs were added.The degree of nervous functional defects was scored for1tim e every day and the observa- tional duration was4 5 days.Results:The total effective rate in TCM WM group was76.2 % butitwas4 7.6% in WM group.In com parison between two groups the difference was significant( P<0 .0 5 ) .The mean tim es to begin with effect〔( 6.94± 1.0 0 ) d〕in TCM WM group were significantly shorter than those〔( 8.2 0± 1.73 ) d〕 in WM group( P<0 .0 5 ) .Conclusions:The curative effects of integrated TCM WM on SIH are significantly better than those of WM alone and the mechanisms may be that this therapy is able to relieve cerebral edem a and to protect cerebral cells.