摘要
胰岛移植的主要适应证为胰岛素依赖型糖尿病（Insulin dependent diabetes mellitus，IDDM），即Ⅰ型糖尿病。众多实验研究证实，胰岛移植可以纠正患者的糖尿病状态，而且可有效地防止糖尿病微血管病变的发生、发展，促进糖代谢内环境稳定，降低死亡率。而胰岛移植由于供体来源、免疫排斥反应制以及胰岛存活时间等将约其发展。本文就胰岛移植在这些方面的进展进行阐述。
出处
《中国伤残医学》
2011年第6期108-109,共2页
Chinese Journal of Trauma and Disability Medicine
参考文献14
-
1Oskor M,Von mering J,Diabetes mellitus nach Pankreasexstirpation [J]. Arch Exppathol Pharmakol,1890,26:37.
-
2Krickhahn M, Meyer T, Buhler C, Thiede A, Ulrichs K. Highly efficient isolation of porcine islets of Langerhans for xenotransplantation: numbers, purity, yield and in vitro function. Ann Transplant 2001 ;6(3):48-54.
-
3Pohajdak B,Mansour M,Hrytsenko O, et al. Production of transgenic Tilapia with Brockmann bodies secreting[desThrB30] human insulin. Transgenic Res, 2004,13(4):313-323.
-
4Ricordi C,Lacy PE,Finke EH,et al. Automated method for isolation of human pancreatic islet [J]. Diabetes, 1988,37(4):413-420.
-
5Kenmochi T,Asano T,Jingu K,et al. Effectiveness of hudrox yethyl starch(HES) on purification of pancreatic islet[J]. J Surg Res,2003, 111 (1): 16-22.
-
6Bottino R,Lehmann R. Improved human islet isolation using a new enzyme blend ,liberase[J]. Diabetes, 1997,46(7): 1120-1123.
-
7Maki T, O'Neil JJ, Porter J, Mullon C J, Solomon BA, Monaco AP. Porcine islets for xenotransplantatian. Transplantation. 1996;62: 136-8.
-
8Friedman T, Smith RN, Colvin RB, Iacomini J. A critical role for human CD4 + T-cells in rejection of porcine islet cell xenografts. Diabetes. 1999;48:2340-8.
-
9Andereggen E, Buhler L, Fournier B, Deng S, Bubloz C, Morel P. Immunohistological study of islet xenograft rejection in immunosuppressed recipients. Transplant Proc 1996 ;28:826-8.
-
10Lehnert AM, Cowan P, Salvaris E, Burgess J, d' Apice AJ F, O' Connell PJ. High titre anti-Ga! antibodies cause islet graft rejection. Presented at the 5th Congress of the International Xenotrans plantation Association, Nagoya, Japan 1999.
同被引文献11
-
1牛德亮,常彩红.人工模拟胰腺微环境诱导骨髓间充质干细胞分化为胰岛素产生细胞[J].郑州大学学报（医学版）,2009,44(5):960-963. 被引量：2
-
2Choi KS,Shin JSiLee JJ,et al. In vitro trans-differentia- tion of rat mesenchymal cells into insulin-producing cells by rat pancreatic extract[J]. Biochem Biophys Res Com- mun,2005,330(4) : 1299-1305.
-
3Xing Y,Xu Q,Ma Y,et al. Effect of porous starch con- centrations on the microbiological characteristics of mi- croencapsulated lactobacillus acidophilus[J]. Food & Func- tion, 2014,5 (5) : 972-983.
-
4Yang YM,Li P,Cui DC,et al. Effect of aged bone marrow microenvironment on mesenchymal stem cell migration[J]. Age (Dordreeht, Netherlands), 2015,37 (2) : 9743.
-
5Jindal RM. The use of zinc binding dyes and fluores- cence-activated islet sorters[J]. Pancreas, 1995,11 (3) : 316- 318.
-
6Solomon TP, Malin SK, Karstoft K, et al. Determining pan- creatic G-cell compensation for changing insulin sensitiv- ity using an oral glucose tolerance test[J]. Am J Physiol Endocrinol Metab, 2014,307 (9) : E822-829.
-
7Yu Q,Liu L,Lin J,et al. SDF-lc~/CXCR4 axis mediates the migration of mesenehymal stem cells to the hypoxie- isehemie brain lesion in a rat model[J]. Cell J,2015,16 (4) :440-447.
-
8Borkowska P, Fila-Danilow A, Paul-Samojedny M, et al. Differentiation of adult rat mesenchymal stem cells to gabaergic,dopaminergic and cholinergic neurons[J]. Phar- macol Rep,2015,67(2) : 179-186.
-
9Grigore A,Sarker B,Farbry B,et al. Behavior of encap- sulated MG-63 cells in RGD and gelatine-modified al- ginate hydrogels[J]. Tissue Eng Part A, 2014,20(15-16) : 2140-2150.
-
10穆长征,李宏丹,蔡红玉.尼克酰胺与胰腺损伤提取物诱导小鼠骨髓间充质干细胞分化为胰岛素产生细胞的比较[J].解剖学报,2010,41(6):852-856. 被引量：7
-
1周风霞.Ⅰ型糖尿病患者血浆纤维蛋白原及血糖的改变[J].微循环学杂志,2006,16(4):78-78.
-
2任小琴,刘静.儿童糖尿病酮症酸中毒1例抢救护理体会[J].现代医药卫生,2004,20(16):1684-1685.
-
3张运斌,潘大虎,王娟.糖尿病患者的血磷分析[J].实用临床医学（江西）,2001,15(A02):60-61. 被引量：1
-
4金丹.应用奥伦自理模式对1型糖尿病儿童的护理[J].现代医药卫生,2011,27(5):765-766.
-
5卞月秋.糖尿病肾病护理[J].内蒙古中医药,2012,31(16):128-129.
-
6齐少芹.儿童糖尿病酮症1例护理体会[J].淮海医药,2008,26(5):460-460. 被引量：2
-
7范伟萍,刘奉玲,王芳.糖尿病肾衰肾移植术患者2例的护理[J].解放军护理杂志,2001,18(6):55-56.
-
8张然.健康教育在胰岛素依赖型糖尿病护理中的应用[J].卫生职业教育,2002,20(11):66-67.
-
9靳淑玲,李彩,王北宁,肖岩.血清胰岛细胞抗体胰岛素抗体检测的临床意义[J].解放军医药杂志,1997,19(5):390-391.
-
10潘冬梅.糖尿病的护理[J].职业与健康,2006,22(14):1130-1131. 被引量：13
