回顾性分析本院用更昔洛韦与阿昔洛韦治疗单纯疱疹病毒性角膜炎的疗效

Retrospective analysis the effecs of ganciclovir and acyclovir in the treatment of patients with herpes simplex keratitis in our hospital

目的回顾性分析本院用更昔洛韦与阿昔洛韦治疗单纯疱疹病毒性角膜炎的疗效。方法收集近年在本院门诊就诊的100例(106眼)单纯疱疹病毒性角膜炎患者,其中48例用更昔洛韦眼用凝胶;37例用阿昔洛韦眼液。比较两者疗效。结果更昔洛韦组与阿昔洛韦组总有效率分别为91.7%,75.7%,显示更昔洛韦眼用凝胶的有效率好于阿昔洛韦眼液(P<0.05)。结论更昔洛韦眼用凝胶治疗单纯疱疹病毒性角膜炎的效果较好。

Objective Retrospective comparison and analysis the effects of ganciclovir and acyclovir in treatment for patients with herpes simplex keratitis in our hospital.Methods One hundred patients with herpes simplex keratitis were analyzed retrospectively in recent years.Fourty-eight cases were treated by ganciclovir ophthalmic gel,whereas 37 cases were treated by acyclovir eye drops.The effects of two kinds of drugs was compared.Results The total rate of effectiveness in ganciclovir group was 91.7%.The rate in ganciclovir group was 75.7%.The efficiency rate of ganciclovir ophthalmic gel is higher than acyclovir eye drops（P0.05）.Conclusion Herpes simplex keratitis is one of the eye diseases which can grow blind.Ganciclovir ophthalmic gel is much better on effects than acyclovir eye drops.