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线粒体膜通透性转运孔的研究进展及其心肌保护策略 被引量:4

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摘要 早在1976年,线粒体膜通透性转运(MPT)被研究者首次报道,该现象是指线粒体内膜对离子和溶质通透性突然增加.而MPT的发生决定于线粒体膜通透性转运孔(MPTP)的开放,MPTP是位于线粒体内外膜交接处的高通透性孔道,具有非特异性通透及可调控性开放的特点,完全开放时允许相对分子质量小于1 500的分子自由扩散.
作者 刘亚华 沈洪
出处 《中国危重病急救医学》 CAS CSCD 北大核心 2011年第6期381-384,共4页 Chinese Critical Care Medicine
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