无创正压通气在慢性阻塞性肺疾病合并肺性脑病时的临床应用

Clinical application noninvasive positive pressure ventilation in chronic obstructive pulmonary disease with pulmonary encephalopathy

目的探讨无创双水平正压通气(BiPAP)治疗慢性阻塞性肺疾病合并肺性脑病的临床疗效。方法选择慢性阻塞性肺疾病合并肺性脑病患者80例,随机分为对照组和治疗组,对照组采用常规治疗,治疗组在常规治疗基础上采用无创BiPAP治疗,观察两组患者治疗48h后临床症状改善情况,记录两组治疗前后血气指标。结果治疗组临床症状改善情况和治疗前后血气指标变化情况均优于对照组(P<0.01)。结论在常规治疗基础上,采用无创BiPAP治疗慢性阻塞性肺疾病并肺性脑病临床效果显著,值得推广应用。

Objective To investigate the clinical effects of non-invasive bi-level positive airway pressure（BiPAP） treatment of chronic obstructive pulmonary disease with pulmonary encephalopathy patients.Methods Chronic obstructive pulmonary disease with pulmonary encephalopathy in 80 patients were randomly divided into control and treatment groups,control group were treated with conventional therapy,the treatment group were based on the use of non-invasive treatment of BiPAP therapy,patients were observed 48h improvement of clinical symptoms,blood gas before and after treatment of the two groups.Results The clinical symptoms and changes in blood gas before and after treatment were better than that of the control group（P0.01）.Conclusions The conventional treatment,based on a non-invasive BiPAP treatment for chronic obstructive pulmonary disease and pulmonary encephalopathy have significant effect,should be widely applied.