摘要
目的：探讨特比萘芬口服联合联苯苄唑乳膏外用治疗足癣的临床疗效。方法：本研究足癣患者共1zO例，随机分为实验组与对照组，其中实验组采用特比萘芬口服联合联苯苄唑乳膏外用，对照组采用联苯苄唑乳膏外用，观察两组临床疗效、真菌学疗效及安全性。结果：治疗第2、4周两组患者总有效率、真菌清除率差异均无统计学意义（P〉0．05），而第12、24周总有效率差异具有统计学意义（P〈0．05）；第24周真菌清除率差异也具有统计学意义（P〈0．05）；出现3例轻度不良反应。结论：采用特比萘芬口服联合联苯苄唑乳膏外用治疗足癣，可获得有效的临床疗效及安全性，在临床上值得推广应用。
Aim： To learn the clinic effect of tinea pedis with Terbinafine and bifonazole cream. Methods： 120 patients of tinea pedis divided into 2 groups. The experimental group uses oral Terbinafine and external bifonazole cream while control group uses external bifonazole cream. Results： The total effective rate and mycological clearance of 2 groups in 2w and 4w has not significance （P〉0.05）. The total effective rate in 12w and 24w has significance （P〈0.05）. The mycological clearance in 24w has significance （P〈0.05）. 3 patients have mild untoward effect. Conclusion： Oral Terbinafine and external bifonazole cream is used for tinea pedis have excellent effect and safety, worth using widely.
