精氨酸辅助治疗肝性脑病的临床效果观察

目的：探讨精氨酸在肝性脑病患者的辅助治疗的临床效果.方法：将我院2009年1月～2010年5月收治的154例肝硬化并发肝性脑病的患者随机分为3组,I组患者给予单纯纳洛酮进行治疗,II组患者给予单纯精氨酸治疗,III组患者给予精氨酸辅助纳洛酮治疗,3组患者其他综合治疗方案相同.观察3组患者的临床疗效,并对结果进行统计学分析.结果：I组患者总有效率为64.71%,II组患者总有效率为68.63%,III组患者的总有效率为90.38%.III组明显优于I组和II组,经统计学分析,p＜0.05.结论：精氨酸辅助治疗肝硬化合并肝性脑病有较好的疗效,可促进患者清醒,值得在临床推广应用.

Objective Of Arginine in hepatic eneephalopathy in patients with the clinical effects of adjuvant therapy. Methods To our hospital in January 2009 - May 2010 154 patients were treated with hepatic encephalopathy complicated with liver cirrhosis were randomly divided into 3 groups, I group were treated with naloxone treatment alone, II group were treated with pure Arginlne Treatment, III group were treated with Arginine supporting naloxone, 3 groups were the same as other comprehensive treatment program. Observe the clinical eIficacy of 3 groups, and the results were statistically analyzed. Result The total effective rate of the patients f 64.71%, II total effective rate of patients 68.63%, III patients, the total effective rate was 90.38%. Group III was significantly better than I and II groups, the statistical analysis, p d0.05. Conclusion Arginine adjuvant treatment of liver cirrhosis with hepatic encephalopathy has a good effect, can promote the patient awake, and worth of clinical application.