完全胃肠外营养及早期肠内营养对重症急性胰腺炎的疗效比较

Comparison of Effect on The Treatment of Severe Acute Pancreatitis Between Total Parenteral Nutrition And Early Enteral Nutrition

目的:比较经鼻空肠管行肠内营养(EN)与完全胃肠外营养在重症急性胰腺炎(SAP)的应用效果。方法:将70例SAP患者随机分为肠内营养(EN)组和完全胃肠外营养(TPN)组,分别比较2组患者治疗前及治疗后第7、14d的血淀粉酶(AMS)、血清C反应蛋白(CRP)和白蛋白等指标,及并发症及感染的发生率、死亡率、住院时间和费用、SPACHE-Ⅱ等指标。结果:EN组CRP降低及血清白蛋白升高程度显著大于TPN组,感染及死亡率、住院时间及费用均小于TPN组,治疗后APACHE-Ⅱ明显降低。结论:EN为SAP的重要治疗手段,合理应用能明显改善预后。

Objective：To compare the effect between total parenteral nutrition（TPN） and early enteral nutrition（EN） for severe acute pancreatitis（SAP）.Methods：All 70 cases were randomly divided into EN group and TPN group,these targets,such as AMS,CRP, albumen,eom plication,death rate,length of stay, SPACHE-II ,and so on,were compared after being tereted 7,14 days.Results：EN group had better treatment effect to CRP, albumen than TPN group,the death rate,length of stay and cost was smaller than TPN group.Conelusion：EN was a key treatment method for SAP, could improve progn.by reasonable application.