长春地区冬季儿童上呼吸道感染病毒病原学检测结果分析

Analysis on Viral Etiology of Children with Upper Respiratory Infection in Changchun Area

目的了解长春地区冬春季急性上呼吸道感染患儿6种呼吸道病毒感染情况。方法采集门诊119例患儿咽拭子,应用(RT)-PCR方法检测甲型流感病毒(IVA)、A亚型呼吸道合胞病毒(RSVA)、副流感病毒(PIV)3型、腺病毒(ADV)、博卡病毒(HBoV)以及人偏肺病毒(hMPV)等6种常见呼吸道病毒。结果检测出阳性标本53例,阳性率44.54%,以流感病毒最高(19.33%)。经χ2检验,病毒总检出率在性别间差异有统计学意义(χ2=7.96,P<0.05)。结论流感病毒是长春地区2008年冬季患儿急性上呼吸道感染的主要病毒病原,男性患儿较女性患儿对呼吸道病毒易感。

Objective To know six kinds of respiratory viral infection in children suffered from acute upper respiratory tract infection in Changchun area winter and spring.Methods 119 out-patients in children were selected and throat swab samples were collected,（RT）-PCR method was applied to detect six kinds of common respiratory viruses including influenza A virus（IVA）,respiratory syncytial virus subgroup A（RSVA）,parainfluenza virus（PIV） type 3,adenovirus（ADV）,human bocavirus（HBoV） and human metapneumovirus（hMPV）.Results 53 positive samples was detected,the positive rate was 44.54%,influenza virus was the highest in them（19.33%）.The total detection rate of the virus between genders had statistically significant difference（χ^2=7.96,P0.05）.Conclusion Influenza virus is the major viral pathogen in children with acute upper respiratory tract infection in Changchun 2008 winter,male children are more susceptible to the respiratory viruses.