普鲁卡因联合肾上腺色腙治疗肺结核大咯血疗效观察

The effect of procaine combined with carbazochrome on moderate to massive hemoptysis due to tuberculosis

目的观察普鲁卡因联合肾上腺色腙治疗肺结核大咯血的临床疗效和不良反应。方法 108例大咯血的肺结核患者随机分为对照组和治疗组两组。对照组53例患者用垂体后叶素,治疗组55例患者用普鲁卡因联合肾上腺色腙,观察两组治疗48小时后的疗效。结果对照组有效率为81.13%,治疗组有效率为96.36%,治疗组止血效果明显优于对照组,统计有明显差异(P<0.05),对照组不良反应显著高于治疗组。结论普鲁卡因联合肾上腺色腙治疗肺结核中大量咯血疗效比垂体后叶素止血效果好,不良反应少,可在临床推广应用。

Objective To observe the efficacy and adverse effects of procaine combined with carbazochrome in treating moderate to massive hemoptysis due to tuberculosis.Methods 108 patients with moderate to massive hemoptysis due to tuberculosis were randomized divided into receive either vasopressin（53 patients） or procaine and carbazochrome（55 patients） treatments.Results The total effective rates of coutrol group and treatment group was 81.13% and 96.36%,respectively（P0.05）.The incidence of adverse effects in vassopressin treating group was significantly higher than that in the procaine and carbazochrome group.Conclusion Procaine and carbazochrome results in better efficacy and less adverse effects in treating moderate to massive hemoptysis than vasopressin.